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An extreme increase in activity and talking mania New or worse anxiety Other unusual changes in behavior or mood New or worse depression How can I watch for early symptoms of suicidal thoughts or actions? Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings.

Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you are worried about symptoms. Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.

Have an eye problem called acute narrow-angle glaucoma. Before using VALTOCO, tell your healthcare provider about all of your medical conditions, including if you: Have asthma, emphysema, bronchitis, chronic obstructive pulmonary disease, or other breathing problems.

Have a history of alcohol or drug abuse. Have a history of depression, mood problems, or suicidal thoughts or behavior. Have liver or kidney problems.

Are pregnant or plan to become pregnant. Are breastfeeding or plan to breastfeed. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Do not test or prime the nasal spray before use. Use all of the medicine in 1 pack for a complete dose. Keep or move the person onto their side. Call for emergency help if any of the following happen: Seizure behavior is different than other seizures the person has had. You are alarmed by how often the seizures happen, by how severe the seizure is, by how long the seizure lasts, or by the color or breathing of the person. Do not drink alcohol or take opioid medicines that make you sleepy or dizzy while taking VALTOCO until you talk to your healthcare provider.

Call your healthcare provider for medical advice about side effects. You may report side effects to Neurelis, Inc. Please see full Prescribing Information and Medication Guide for additional important safety information. Tell your healthcare provider if you have abused or been dependent on alcohol, prescription drugs, or street drugs. Taking benzodiazepines with opioid medicines, alcohol, or other central nervous system depressants including street drugs can cause severe drowsiness, breathing problems respiratory depression , coma, and death.

Call a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you: Thoughts about suicide or dying Feeling agitated or restless Acting aggressive, being angry, or violent Attempts to commit suicide.



For the treatment of status epilepticus or for treatment of drug-induced seizures. Moderate Methyldopa infromation associated with sedative effects. If a benzodiazepine is necessary, a dosage adjustment of the multi-day regimen may be necessary depending on the clinical situation e. Oxazepam and temazepam plasma concentrations are usually undetectable.

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Diazepam Rectal Gel

Diastat Description Diazepam rectal gel rectal delivery system is a non-sterile diazepam gel provided in a prefilled, unit-dose, rectal delivery system. Diazepam rectal gel is clear to slightly yellow and has a pH between 6. Diazepam, the active ingredient of diazepam rectal gel, is a benzodiazepine anticonvulsant with the chemical name 7-chloro-1,3-dihydromethylphenyl-2H-1,4-benzodiazepinone. GABA, the major inhibitory neurotransmitter in the central nervous system, acts at this receptor to open the membrane channel allowing chloride ions to flow into neurons.

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